Article
CTNNB1 (beta-catenin) mutation identifies low grade, early stage endometrial cancer patients at increased risk of recurrence.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jul 2017
Kurnit Katherine C, Kim Grace N, Fellman Bryan M, Urbauer Diana L, Mills Gordon B, Zhang Wei, Broaddus Russell R
Abstract excerpt
Although the majority of low grade, early stage endometrial cancer patients will have good survival outcomes with surgery alone, those patients who do recur tend to do poorly. Optimal identification of the subset of patients who are at high risk of recurrence and would benefit from adjuvant treatment has been difficult. The purpose of this study was to evaluate the impact of somatic tumor mutation on survival...
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