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Genetic variants related to urate and risk of Parkinson's disease.

Parkinsonism & related disorders - 1 Aug 2018

Hughes Katherine C, Gao Xiang, O'Reilly Eilis J, Kim Iris Y, Wang Molin, Weisskopf Marc G, Schwarzschild Michael A, Ascherio Alberto

Abstract excerpt

INTRODUCTION: Higher urate concentrations have been associated with a lower risk of developing Parkinson's disease (PD) and with slower rates of clinical decline in PD patients. Whether these associations reflect a neuroprotective effect of urate is unclear. Our objective was to assess whether genetic variants that modify circulating urate levels are also associated with altered PD risk. METHODS: Participants...

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PMID: 29789205
DOI: 10.1016/j.parkreldis.2018.04.031
PMCID: PMC6120767

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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