Article
Variation in the uric acid transporter gene SLC2A9 and its association with AAO of Parkinson's disease.
Journal of molecular neuroscience : MN - 1 Mar 2011
Facheris Maurizio F, Hicks Andrew A, Minelli Cosetta, Hagenah Johann M, Kostic Vladimir, Campbell Susan, Hayward Caroline, Volpato Claudia B, Pattaro Cristian, Vitart Veronique, Wright Alan, Campbell Harry, Klein Christine, Pramstaller Peter P
Abstract excerpt
Based on the observed inverse association between hyperuricemia and Parkinson's disease (PD) risk, the natural antioxidant activity of uric acid has been suggested to play a protective role. SLC2A9 has been indicated as the most effective of all uric acid transporters, and SLC2A9 variants have been shown to influence circulating uric acid levels. With this study, we aimed to test the association between such...
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