Article
Novel insights into transcriptional dysregulation in colorectal cancer.
Neoplasma - 14 Mar 2018
Feodorova Y, Tashkova D, Koev I, Todorov A, Kostov G, Simitchiev K, Belovejdov V, Dimov R, Sarafian V
Abstract excerpt
Colorectal cancer (CRC) is a leading cause of cancer-related mortality worldwide. Although CRC has been comprehensively characterized at the molecular level, the tumor heterogeneity hinders the identification of reliable diagnostic, prognostic and predictive biomarkers. Molecular stratification of CRC is based on prevalent gene mutations and transcription profiles but its significance for clinical practice...
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