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Article

Landscape of transcriptome variations uncovering known and novel driver events in colorectal carcinoma.

Scientific reports - 16 Jan 2020

Pira Giovanna, Uva Paolo, Scanu Antonio Mario, Rocca Paolo Cossu, Murgia Luciano, Uleri Elena, Piu Claudia, Porcu Alberto, Carru Ciriaco, Manca Alessandra, Persico Ivana, Muroni Maria Rosaria, Sanges Francesca, Serra Caterina, Dolei Antonia, Angius Andrea, De Miglio Maria Rosaria

Abstract excerpt

We focused on an integrated view of genomic changes in Colorectal cancer (CRC) and distant normal colon tissue (NTC) to test the effectiveness of expression profiling on identification of molecular targets. We performed transcriptome on 16 primary coupled CRC and NTC tissues. We identified pathways and networks related to pathophysiology of CRC and selected potential therapeutic targets. CRC cells have multiple...

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Identifiers

PMID: 31949199
DOI: 10.1038/s41598-019-57311-z
PMCID: PMC6965099

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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