Current Challenges in Chronic Graft-versus-Host Disease

Abstract excerpt

Chronic graft-versus-host disease (cGVHD), a multiorgan disorder, is the leading cause of late nonrelapse mortality (NRM) after hematopoietic stem cell transplantation (HSCT). Despite many years of experience with this disease we are still faced with numerous challenges including (among others); lack of reliable preclinical models, poor knowledge of human pathophysiology, validated diagnostic and severity...

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