Article
A Genetic Susceptibility Mechanism for Major Depression: Combinations of polymorphisms Defined the Risk of Major Depression and Subpopulations.
Medicine - 1 Jun 2015
Wang Yanfang, Sun Ning, Li Suping, Du Qiaorong, Xu Yong, Liu Zhifeng, Zhang Kerang
Abstract excerpt
Major Depression (MD) is a highly inherited psychiatric disorder. The norepinephrine transporter (NET) gene plays important role in pathophysiology of MD. This study attempted to examine the relationship between polymorphisms of NET gene and MD. Patients with MD and healthy controls were recruited and subgrouped. The T-182C and G1287A polymorphisms of NET gene were genotyped by direct sequencing. The genotypic...
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