Article
Serum 6-Bromotryptophan Levels Identified as a Risk Factor for CKD Progression.
Journal of the American Society of Nephrology : JASN - 1 Jul 2018
Tin Adrienne, Nadkarni Girish, Evans Anne M, Winkler Cheryl A, Bottinger Erwin, Rebholz Casey M, Sarnak Mark J, Inker Lesley A, Levey Andrew S, Lipkowitz Michael S, Appel Lawrence J, Arking Dan E, Coresh Josef, Grams Morgan E
Abstract excerpt
Background Metabolite levels reflect physiologic homeostasis and may serve as biomarkers of disease progression. Identifying metabolites associated with APOL1 risk alleles-genetic variants associated with CKD risk commonly present in persons of African descent-may reveal novel markers of CKD progression relevant to other populations.Methods We evaluated associations between the number of APOL1 risk alleles and...
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