Article
Urine 6-Bromotryptophan: Associations with Genetic Variants and Incident End-Stage Kidney Disease.
Scientific reports - 22 Jun 2020
Sekula Peggy, Tin Adrienne, Schultheiss Ulla T, Baid-Agrawal Seema, Mohney Robert P, Steinbrenner Inga, Yu Bing, Luo Shengyuan, Boerwinkle Eric, Eckardt Kai-Uwe, Coresh Josef, Grams Morgan E, Kӧttgen Anna
Abstract excerpt
Higher serum 6-bromotryptophan has been associated with lower risk of chronic kidney disease (CKD) progression, implicating mechanisms beyond renal clearance. We studied genetic determinants of urine 6-bromotryptophan and its association with CKD risk factors and incident end-stage kidney disease (ESKD) in 4,843 participants of the German Chronic Kidney Disease (GCKD) study. 6-bromotryptophan was measured from...
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