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Article

Oxime-assisted reactivation of tabun-inhibited acetylcholinesterase analysed by active site mutations.

Toxicology - 1 Aug 2018

Katalinić Maja, Šinko Goran, Maček Hrvat Nikolina, Zorbaz Tamara, Bosak Anita, Kovarik Zrinka

Abstract excerpt

The antidotal property of oximes is attributed to their ability to reactivate acetylcholinesterase (AChE) inhibited by organophosphorus compounds (OP) such as pesticides and nerve warfare agents. Understanding their interactions within the active site of phosphylated AChE is of great significance for the search for more efficient reactivators, especially in the case of the most resistant OP to reactivation,...

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Source

Identifiers

PMID: 29772260
DOI: 10.1016/j.tox.2018.05.008

Genes

PAM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Oxime-assisted reactivation of tabun-inhibited acetylcholinesterase analysed by active site mutations.PMID 29772260Read ↗

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