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Genomic epidemiology and evolution of Bordetella pertussis under the vaccination pressure of acellular vaccines in Beijing, China, 2020-2023.

Emerging microbes & infections - 1 Dec 2025

Li Zhen, Xiao Fei, Hou Yue, Jia Bin, Zhuang Ji, Cao Yang, Ma Jianxin, Zhao Jianhong, Xu Zengquan, Jia Zhe, Liu Fang, Pang Lin, Liu Jie

Abstract excerpt

Pertussis (or whooping cough) has experienced a global resurgence despite widespread vaccine efforts. In China, the incidence of pertussis has rapidly increased, particularly following the COVID-19 pandemic. Whole-genome sequencing analysis was performed on 60 Bordetella pertussis strains isolated in Beijing from 2020-2023, and the sequences were compared with those of 635 strains from China and 943 strains from...

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PMID: 39725566
DOI: 10.1080/22221751.2024.2447611

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