Article
Global methylation profiles in buccal cells of long-term smokers and moist snuff consumers.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Nov 2018
Jessen Walter J, Borgerding Michael F, Prasad G L
Abstract excerpt
PURPOSE: Alternations in gene methylation and other epigenetic changes regulate normal development as well as drive disease progression. The aim of this study is to investigate global methylation changes in the buccal cells of smokers and smokeless tobacco users. MATERIALS AND METHODS: Generally healthy adult male subjects were recruited into smoker (SMK), moist snuff consumer (MSC) and non-tobacco consumer (NTC)...
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