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Article

Smoking-Associated Site-Specific Differential Methylation in Buccal Mucosa in the COPDGene Study

18 Dec 2014

Abstract excerpt

DNA methylation is a complex, tissue-specific phenomenon that can reflect both endogenous factors and exogenous exposures. Buccal brushings represent an easily accessible source of DNA, which may be an appropriate surrogate tissue in the study of environmental exposures and chronic respiratory diseases. Buccal brushings were obtained from a subset of current and former smokers from the COPDGene study. Genome-wide...

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PMID: 25517428
DOI: 10.1165/rcmb.2014-0103oc

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