Article

The molecular impact of cigarette smoking resembles aging across tissues

2024-03-16

Abstract excerpt

Tobacco smoke is the main cause of preventable mortality worldwide. Smoking increases the risk of developing many diseases and has been proposed as an aging accelerator. Yet, the molecular mechanisms driving smoking-related health decline and aging acceleration in most tissues remain unexplored. Here, we characterize gene expression, alternative splicing, DNA methylation and histological alterations induced by cig...

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Literature Corpus work: aaef35e4-865e-5cec-8f9d-616ab7eadf22
DOI: 10.1101/2024.03.14.585016

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