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The relationship of smoking to cg05575921 methylation in blood and saliva DNA samples from several studies

3 Nov 2021

Abstract excerpt

Numerous studies have shown that cg05575921 methylation decreases in response to smoking. However, secondary to methodological issues, the magnitude and dose dependency of that response is as of yet unclear. This lack of certainty is a barrier to the use of DNA methylation clinically to assess and monitor smoking status. To better define this relationship, we conducted a joint analysis of methylation sensitive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34732805
DOI: 10.1038/s41598-021-01088-7

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