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Article

Condensin I protects meiotic cohesin from WAPL-1 mediated removal.

PLoS genetics - 1 May 2018

Hernandez Margarita R, Davis Michael B, Jiang Jianhao, Brouhard Elizabeth A, Severson Aaron F, Csankovszki Györgyi

Abstract excerpt

Condensin complexes are key determinants of higher-order chromatin structure and are required for mitotic and meiotic chromosome compaction and segregation. We identified a new role for condensin in the maintenance of sister chromatid cohesion during C. elegans meiosis. Using conventional and stimulated emission depletion (STED) microscopy we show that levels of chromosomally-bound cohesin were significantly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 29768402
DOI: 10.1371/journal.pgen.1007382
PMCID: PMC5973623

Genes

WAPL
SYP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Condensin I protects meiotic cohesin from WAPL-1 mediated removal.PMID 29768402Read ↗

Condensin restructures chromosomes in preparation for meiotic divisions.Semantic proximity Read ↗

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Genome-wide analysis of condensin binding in Caenorhabditis elegans.Semantic proximity Read ↗

SYP-3 restricts synaptonemal complex assembly to bridge paired chromosome axes during meiosis in Caenorhabditis elegans.Semantic proximity Read ↗

The kleisin subunit controls the function of meiotic cohesins by determining the mode of DNA binding and differential regulation by SCC-2 and WAPL-1Semantic proximity Read ↗

Synaptonemal complex proteins direct and constrain the localization of crossover-promoting proteins during <i>Caenorhabditis elegans</i> meiosisSemantic proximity Read ↗

Condensins regulate meiotic DNA break distribution, thus crossover frequency, by controlling chromosome structure.Semantic proximity Read ↗

Cooperation between Caenorhabditis elegans COMPASS and condensin in germline chromatin organizationSemantic proximity Read ↗

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HTP-1 coordinates synaptonemal complex assembly with homolog alignment during meiosis in C. elegans.Semantic proximity Read ↗

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