Article
Ethnicity-specific impact of HLA I/II genotypes on the risk of inhibitor development: data from Korean patients with severe hemophilia A.
Annals of hematology - 1 Sept 2018
Kim Hyun-Young, Cho Jin-Hee, Kim Hee-Jung, Chung Hae-Sun, Kim Sun-Hee, Lee Ki-O, Jung Soo-Young, Yoo Ki-Young, Kim Hee-Jin
Abstract excerpt
Inhibitor development is the most serious complication in patients with hemophilia. We investigated association of HLA genotypes with inhibitor development in Korean patients with severe hemophilia A (HA). HLA genotyping was done in 100 patients with severe HA including 27 patients with inhibitors. The allele frequencies between inhibitor-positive and inhibitor-negative patients were compared. HLA class I alleles...
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