Article
Influence of class I and II HLA alleles on inhibitor development in severe haemophilia A patients from the south of Brazil.
Haemophilia : the official journal of the World Federation of Hemophilia - 1 May 2012
De Barros M F, Herrero J C M, Sell A M, De Melo F C, Braga M A, Pelissari C B, Machado J, De Souza Schiller S, De Souza Hirle L, Visentainer J E L
Abstract excerpt
Congenital haemophilia A is a chromosome-linked recessive disorder caused by the deficiency or reduction of factor VIII (FVIII) pro-coagulant activity. During treatment, some patients develop alloantibodies (FVIII inhibitors) that neutralize the action of exogenously administered FVIII. Currently...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.