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Article

Risk factors associated with inhibitor development in Chinese patients with haemophilia B.

Haemophilia : the official journal of the World Federation of Hemophilia - 1 Jul 2015

Zhou J, Ding Q, Chen Z, Yang H, Lin L, Wang H, Wang X, Wu R

Abstract excerpt

INTRODUCTION: Inhibitor development is a severe complication of factor IX substitution treatment for haemophilia B (HB). Current research examined the association between inhibitor development and F9 genotypes and polymorphisms in immune response genes in Chinese HB patients. MATERIALS AND METHODS: 11 inhibitor-positive HB patients and 41 inhibitor-negative HB patients were enrolled. Direct sequencing, copy...

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PMID: 25929987
DOI: 10.1111/hae.12684

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