Article
Polygenic pleiotropy and potential causal relationships between educational attainment, neurobiological profile, and positive psychotic symptoms.
Translational psychiatry - 16 May 2018
Lin Yen-Feng, Chen Chia-Yen, Öngür Dost, Betensky Rebecca, Smoller Jordan W, Blacker Deborah, Hall Mei-Hua
Abstract excerpt
Event-related potential (ERP) components have been used to assess cognitive functions in patients with psychotic illness. Evidence suggests that among patients with psychosis there is a distinct heritable neurophysiologic phenotypic subtype captured by impairments across a range of ERP measures. In this study, we investigated the genetic basis of this "globally impaired" ERP cluster and its relationship to...
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