Article
Short article: Influence of regulatory NLRC5 variants on colorectal cancer survival and 5-fluorouracil-based chemotherapy.
European journal of gastroenterology & hepatology - 1 Aug 2018
Catalano Calogerina, da Silva Filho Miguel I, Jiraskova Katerina, Vymetalkova Veronika, Levy Miroslav, Liska Vaclav, Vycital Ondrej, Naccarati Alessio, Vodickova Ludmila, Hemminki Kari, Vodicka Pavel, Weber Alexander N R, Försti Asta
Abstract excerpt
BACKGROUND: NLRC5 is an interferon γ-inducible protein, which plays a role in immune surveillance with a potential influence on cancer survival. OBJECTIVE: We aimed to evaluate the effect of potential regulatory variants in NLRC5 on overall survival and survival after 5-fluorouracil (5-FU)-based therapy of colorectal cancer (CRC) patients. PATIENTS AND METHODS: We carried out a case-only study in a Czech...
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