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Article

Phenotype of neurons in the nucleus of the solitary tract that express CCK-induced activation of the ERK signaling pathway.

American journal of physiology. Regulatory, integrative and comparative physiology - 1 Apr 2009

Babic Tanja, Townsend R Leigh, Patterson Laurel M, Sutton Gregory M, Zheng Huiyuan, Berthoud Hans-Rudolf

Abstract excerpt

The satiating potency of CCK has been well characterized, including its mediation by capsaicin-sensitive vagal primary afferents. We have previously shown that peripherally administered CCK activates the MAPK-signaling cascade in a population of nucleus of the solitary tract (NTS) neurons and that preventing ERK1/2 phosphorylation partly attenuates CCK's satiating potency. The aim of this study was to identify...

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Source

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Identifiers

PMID: 19176891
DOI: 10.1152/ajpregu.90531.2008
PMCID: PMC4043315

Genes

CCK
NTS
POMC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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