Formation of dominant mode by evolution in biological systems.

doi:10.1103/PhysRevE.97.042410

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Article

Formation of dominant mode by evolution in biological systems.

Physical review. E - 1 Apr 2018

Furusawa Chikara, Kaneko Kunihiko

Abstract excerpt

A reduction in high-dimensional phenotypic states to a few degrees of freedom is essential to understand biological systems. Here, we show evolutionary robustness causes such reduction which restricts possible phenotypic changes in response to a variety of environmental conditions. First, global protein expression changes in Escherichia coli after various environmental perturbations were shown to be proportional...

Topics

Adaptation, Physiological
Biological Evolution
Escherichia coli
Escherichia coli Proteins
Models, Biological
Phenotype

Source

Open in PubMed

Identifiers

PMID: 29758752
DOI: 10.1103/PhysRevE.97.042410

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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