Article
A minimal and self-consistent in silico cell model based on macromolecular interactions.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 29 Oct 2007
Flamm Christoph, Endler Lukas, Müller Stefan, Widder Stefanie, Schuster Peter
Abstract excerpt
A self-consistent minimal cell model with a physically motivated schema for molecular interaction is introduced and described. The genetic and metabolic reaction network of the cell is modelled by multidimensional nonlinear ordinary differential equations, which are derived from biochemical kinet...
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