Article
Robustness and evolvability in genetic regulatory networks.
Journal of theoretical biology - 7 Apr 2007
Aldana Maximino, Balleza Enrique, Kauffman Stuart, Resendiz Osbaldo
Abstract excerpt
Living organisms are robust to a great variety of genetic changes. Gene regulation networks and metabolic pathways self-organize and reaccommodate to make the organism perform with stability and reliability under many point mutations, gene duplications and gene deletions. At the same time, living organisms are evolvable, which means that these kind of genetic perturbations can eventually make the organism acquire...
Topics
- Animals
- Conserved Sequence
- Evolution, Molecular
- Gene Expression Regulation
- Genotype
- Models, Genetic
- Mutation
- Nonlinear Dynamics
- Phenotype
