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Article

Autophagy regulates apoptosis by targeting NOXA for degradation

22 May 2018

Abstract excerpt

Apoptosis and autophagy mutually regulate various cellular physiological and pathological processes. The crosstalk between autophagy and apoptosis is multifaceted and complicated. Elucidating the molecular mechanism of their crosstalk will advance the therapeutic applications of autophagy for treating cancer and other diseases. NOXA, a BH3-only member of the BCL-2 family, was reported to induce apoptosis and...

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PMID: 29758299
DOI: 10.1016/j.bbamcr.2018.05.007

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