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Antiviral Activity of an Indole-Type Compound Derived from Natural Products, Identified by Virtual Screening by Interaction on Dengue Virus NS5 Protein

17 Jul 2023

Abstract excerpt

Dengue is an acute febrile illness caused by the Dengue virus (DENV), with a high number of cases worldwide. There is no available treatment that directly affects the virus or the viral cycle. The objective of this study was to identify a compound derived from natural products that interacts with the NS5 protein of the dengue virus through virtual screening and evaluate its in vitro antiviral effect on DENV-2....

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Computational Drug Discovery Methods
Mosquito-borne diseases and control
vaccines and immunoinformatics approaches

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37515249
DOI: 10.3390/v15071563

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