Article
Comprehensive review of genetic association studies and meta-analysis on miRNA polymorphisms and rheumatoid arthritis and systemic lupus erythematosus susceptibility.
Human immunology - 1 Jan 2016
Fu Lingyu, Jin Lei, Yan Lei, Shi Jingpu, Wang Hailong, Zhou Bo, Wu Xiaomei
Abstract excerpt
BACKGROUND: MicroRNAs (miRNAs), small RNA molecules, play a role in the development and differentiation of immune cells in both innate and adaptive immune responses. Our study was aimed to investigate the association between three miRNA polymorphism and rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) by using meta-analysis approach. METHODS: A PubMed database search was conducted during August...
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