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Article

Drosophila models of amyotrophic lateral sclerosis with defects in RNA metabolism.

Brain research - 15 Aug 2018

Zhang Ke, Coyne Alyssa N, Lloyd Thomas E

Abstract excerpt

The fruit fly Drosophila Melanogaster has been widely used to study neurodegenerative diseases. The conservation of nervous system biology coupled with the rapid life cycle and powerful genetic tools in the fly have enabled the identification of novel therapeutic targets that have been validated in vertebrate model systems and human patients. A recent example is in the study of the devastating motor neuron...

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PMID: 29752901
DOI: 10.1016/j.brainres.2018.04.043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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