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Article

USP18 promotes breast cancer growth by upregulating EGFR and activating the AKT/Skp2 pathway

30 Apr 2018

Abstract excerpt

Recent studies have suggested that ubiquitin-specific peptidase (USP)18 may act as an oncogene in various types of cancer. Although the role of USP18 in breast cancer cell lines has been elucidated, the underlying mechanisms and clinical role of USP18 in breast cancer are currently not well understood. The bioinformatics analysis and experimental results of the present study demonstrated that aberrant promoter...

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Identifiers

PMID: 29749454
DOI: 10.3892/ijo.2018.4387

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