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Article

USP10 as a Potential Therapeutic Target in Human Cancers

6 May 2022

Abstract excerpt

Deubiquitination is a major form of post-translational protein modification involved in the regulation of protein homeostasis and various cellular processes. Deubiquitinating enzymes (DUBs), comprising about five subfamily members, are key players in deubiquitination. USP10 is a USP-family DUB featuring the classic USP domain, which performs deubiquitination. Emerging evidence has demonstrated that USP10 is a...

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PMID: 35627217
DOI: 10.3390/genes13050831

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