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Article

Prognostic implication of PD-L1 polymorphisms in non-small cell lung cancer treated with radiotherapy.

Cancer medicine - 1 Nov 2021

Kang Min Kyu, Lee Shin Yup, Choi Jin Eun, Do Sook Kyung, Cho Moon-June, Kim Jun-Sang, Park Jae Yong

Abstract excerpt

BACKGROUND: To investigate the impact of programmed death-ligand 1 (PD-L1) polymorphisms on the prognosis of non-small cell lung cancer (NSCLC) patients treated with curative radiotherapy. METHODS: Four single nucleotide polymorphisms (SNPs) (rs822336G>C, rs822337T>A, rs822338C>T, and rs2297136A>G) in the PD-L1 gene were evaluated in 124 NSCLC patients. Clinical stage was I in 28, II in 17, and III in 79...

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Identifiers

PMID: 34612596
DOI: 10.1002/cam4.4329
PMCID: PMC8607250

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