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Poly( rC ) binding protein 2 ( PCBP 2) promotes the viability of human gastric cancer cells by regulating CDK2

26 Feb 2018

Abstract excerpt

Survival rates for patients with gastric cancer, especially the advanced form, remain poor and the development of targeted treatments is hampered by a lack of efficient biological targets. Poly(rC) binding protein 2 (PCBP2) is an RNA-binding protein that contributes to mRNA stabilization, translational silencing and enhancement and it has been implicated as a promoter of gastric cancer growth. In the present...

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PMID: 29744291
DOI: 10.1002/2211-5463.12408

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