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Article

Impact of poly(rC)-binding protein 2 (PCBP2) on the malignant phenotype of cholangiocarcinoma.

Biochemical pharmacology - 1 Jul 2026

Reviejo Maria, Lozano Elisa, Mendez Raul, Gonzalez Luis M, Macias Rocio I R, Briz Oscar, Marin Jose J G, Asensio Maitane

Abstract excerpt

Expression of poly(rC)-binding protein 2 (PCBP2) is altered in various cancers. This study aimed to assess its role in the development of the malignant phenotype in cholangiocarcinoma (CCA) cells. PCBP2 mRNA levels in CCA (n = 35) and adjacent non-tumor (NT) tissue (n = 9) were analyzed in silico using the TCGA-CHOL database. PCBP2 expression was also measured experimentally (RT-qPCR, WB, and IHC) in clinical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41876016
DOI: 10.1016/j.bcp.2026.117927

Genes

PCBP2
DHRS3
MEX3A
NRP2
PCGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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