Article
RNA-binding protein RNPC1: acting as a tumor suppressor in breast cancer.
BMC cancer - 7 May 2014
Xue Jin-Qiu, Xia Tian-Song, Liang Xiu-Qing, Zhou Wenbin, Cheng Lin, Shi Liang, Wang Ying, Ding Qiang
Abstract excerpt
BACKGROUND: RNA binding proteins (RBPs) play a fundamental role in posttranscriptional control of gene expression. Different RBPs have oncogenic or tumor-suppressive functions on human cancers. RNPC1 belongs to the RNA recognition motif (RRM) family of RBPs, which could regulate expression of diverse targets by mRNA stability in human cancer cells. Several studies reported that RNPC1 played an important role in...
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