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Article

Inhibitory Effects of HIV-2 Vpx on Replication of HIV-1

7 May 2018

Abstract excerpt

ABSTRACT Human immunodeficiency virus type 1 (HIV-1) and HIV-2 share a striking genomic resemblance; however, variability in the genetic sequence accounts for the presence of unique accessory genes, such as the viral protein X ( vpx ) gene in HIV-2. Dual infection with both viruses has long been described in the literature, yet the molecular mechanism of how dually infected patients tend to do better than those...

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PMID: 29743354
DOI: 10.1128/jvi.00554-18

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