Article
Inhibition of HIV-1 disease progression by contemporaneous HIV-2 infection.
The New England journal of medicine - 19 Jul 2012
Esbjörnsson Joakim, Månsson Fredrik, Kvist Anders, Isberg Per-Erik, Nowroozalizadeh Salma, Biague Antonio J, da Silva Zacarias J, Jansson Marianne, Fenyö Eva Maria, Norrgren Hans, Medstrand Patrik
Abstract excerpt
BACKGROUND: Progressive immune dysfunction and the acquired immunodeficiency syndrome (AIDS) develop in most persons with untreated infection with human immunodeficiency virus type 1 (HIV-1) but in only approximately 20 to 30% of persons infected with HIV type 2 (HIV-2); among persons infected with both types, the natural history of disease progression is poorly understood. METHODS: We analyzed data from 223...
Topics
- Acquired Immunodeficiency Syndrome
- Adult
- CD4 Lymphocyte Count
- CD8-Positive T-Lymphocytes
- Cohort Studies
- Coinfection
- Disease Progression
- Evolution, Molecular
- Female
- Genetic Variation