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Limelight on two HIV/SIV accessory proteins in macrophage infection: Is Vpx overshadowing Vpr?

9 Apr 2010

Abstract excerpt

HIV viruses encode a set of accessory proteins, which are important determinants of virulence due to their ability to manipulate the host cell physiology for the benefit of the virus. Although these viral proteins are dispensable for viral growth in many in vitro cell culture systems, they influence the efficiency of viral replication in certain cell types. Macrophages are early targets of HIV infection which...

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PMID: 20380700
DOI: 10.1186/1742-4690-7-35

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