Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ICAM-1-related long non-coding RNA: promoter analysis and expression in human retinal endothelial cells.

BMC research notes - 9 May 2018

Lumsden Amanda L, Ma Yuefang, Ashander Liam M, Stempel Andrew J, Keating Damien J, Smith Justine R, Appukuttan Binoy

Abstract excerpt

OBJECTIVE: Regulation of intercellular adhesion molecule (ICAM)-1 in retinal endothelial cells is a promising druggable target for retinal vascular diseases. The ICAM-1-related (ICR) long non-coding RNA stabilizes ICAM-1 transcript, increasing protein expression. However, studies of ICR involvement in disease have been limited as the promoter is uncharacterized. To address this issue, we undertook a comprehensive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding Sites
Share to Endothelial Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Intercellular Adhesion Molecule-1

Share to Promoter Regions, Genetic

Share to Protein Binding

Share to Retina

Share to RNA, Long Noncoding

Source

Open in PubMed Open full text

Identifiers

PMID: 29743093
DOI: 10.1186/s13104-018-3384-8
PMCID: PMC5944171

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ICAM-1-related long non-coding RNA: promoter analysis and expression in human retinal endothelial cells.PMID 29743093Read ↗

High-density SNP map of human ITR, a gene associated with vascular remodeling.Semantic proximity Read ↗

Inflammation-Induced Alternative Splicing in Human Endothelial Cells Reveals Genetic Mechanisms of Cardiovascular Disease RiskSemantic proximity Read ↗

Dynamic changes in RNA-chromatin interactome promote endothelial dysfunctionSemantic proximity Read ↗

Structural and Functional Implications of the Intron/Exon Organization of the Human Endothelial Cell Protein C/Activated Protein C Receptor (EPCR) Gene: Comparison With the Structure of CD1/Major Histocompatibility Complex 1 and 2 DomainsSemantic proximity Read ↗

Endothelial long non-coding RNAs regulated by oxidized LDLSemantic proximity Read ↗

Polymorphism in regulatory gene sequences.Semantic proximity Read ↗

Role of six single nucleotide polymorphisms, risk factors in coronary disease, in OLR1 alternative splicing.Semantic proximity Read ↗

Identification and functional characterization of an AMD associated c-ABL binding SNP streak within the ARMS2 gene promoter regionSemantic proximity Read ↗

The human rs1050286 polymorphism alters LOX-1 expression through modifying miR-24 binding.Semantic proximity Read ↗

The Relevance of Genomic Signatures at Adhesion GPCR Loci in Humans.Semantic proximity Read ↗

Genetic variants of VEGFR-1 gene promoter in acute myocardial infarction.Semantic proximity Read ↗

Population- and individual-specific regulatory variation in Sardinia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.