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Article

Genetic variants of VEGFR-1 gene promoter in acute myocardial infarction.

Human genomics - 19 Nov 2019

Wang Haihua, Zhang Shufang, Wang Na, Zhang Jie, Chen Mingkai, He Xiaohui, Cui Yinghua, Pang Shuchao, Yan Bo

Abstract excerpt

BACKGROUND: Coronary artery disease (CAD) including acute myocardial infarction (AMI) is a common complex disease caused by atherosclerosis. Vascular epithelial growth factor receptor-1 (VEGFR-1) stimulates angiogenesis and vascular permeability, and functions as a decoy to sequester VEGF and prevent initiation of intracellular signaling. VEGFR-1 knockout mice exhibit significantly higher mortality due to heart...

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Identifiers

PMID: 31744542
DOI: 10.1186/s40246-019-0243-1
PMCID: PMC6862733

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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