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Article

PDXliver: a database of liver cancer patient derived xenograft mouse models.

BMC cancer - 9 May 2018

He Sheng, Hu Bo, Li Chao, Lin Ping, Tang Wei-Guo, Sun Yun-Fan, Feng Fang-You-Min, Guo Wei, Li Jia, Xu Yang, Yao Qian-Lan, Zhang Xin, Qiu Shuang-Jian, Zhou Jian, Fan Jia, Li Yi-Xue, Li Hong, Yang Xin-Rong

Abstract excerpt

BACKGROUND: Liver cancer is the second leading cause of cancer-related deaths and characterized by heterogeneity and drug resistance. Patient-derived xenograft (PDX) models have been widely used in cancer research because they reproduce the characteristics of original tumors. However, the current studies of liver cancer PDX mice are scattered and the number of available PDX models are too small to represent the...

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Identifiers

PMID: 29743053
DOI: 10.1186/s12885-018-4459-6
PMCID: PMC5944069

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