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Article

Polymorphism in the gene encoding the apical membrane antigen-1 (AMA-1) of Plasmodium falciparum. X. Asembo Bay Cohort Project.

Molecular and biochemical parasitology - 6 Apr 2001

Escalante A A, Grebert H M, Chaiyaroj S C, Magris M, Biswas S, Nahlen B L, Lal A A

Abstract excerpt

We have investigated the genetic diversity of the gene encoding the apical membrane antigen-1 (AMA-1) in natural populations of Plasmodium falciparum from western Kenya and compared it with parasite populations from other geographic regions. A total of 28 complete sequences from Kenya, Thailand, India, and Venezuela field isolates were obtained. The genetic polymorphism is not evenly distributed across the gene,...

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PMID: 11295182
DOI: 10.1016/s0166-6851(01)00229-8

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