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Article

Hippocampal place cell dysfunction and the effects of muscarinic M1 receptor agonism in a rat model of Alzheimer's disease.

Hippocampus - 1 Aug 2018

Galloway Claire R, Ravipati Kaushik, Singh Suyashi, Lebois Evan P, Cohen Robert M, Levey Allan I, Manns Joseph R

Abstract excerpt

Alzheimer's disease (AD) is a neurodegenerative disease that disproportionately impacts memory and the hippocampus. However, it is unclear how AD pathology influences the activity of surviving neurons in the hippocampus to contribute to the memory symptoms in AD. One well-understood connection between spatial memory and neuronal activity in healthy brains is the activity of place cells, neurons in the hippocampus...

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Identifiers

PMID: 29742799
DOI: 10.1002/hipo.22961
PMCID: PMC6133736

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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