Resistance detected in PBMCs predicts virological rebound in HIV-1 suppressed patients switching treatment.

doi:10.1016/j.jcv.2018.04.001

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Resistance detected in PBMCs predicts virological rebound in HIV-1 suppressed patients switching treatment.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jul 2018

Armenia Daniele, Zaccarelli Mauro, Borghi Vanni, Gennari William, Di Carlo Domenico, Giannetti Alberto, Forbici Federica, Bertoli Ada, Gori Caterina, Fabeni Lavinia, Pinnetti Carmela, Marocco Raffaella, Latini Alessandra, Ceccherini-Silberstein Francesca, Mastroianni Claudio Maria, Mussini Cristina, Antinori Andrea, Perno Carlo Federico, Santoro Maria Mercedes

Abstract excerpt

BACKGROUND: Genotypic resistance test (GRT) performed in peripheral blood mononuclear cells (PBMC) represents a chance to evaluate resistance in virologically suppressed HIV infected patients. OBJECTIVES: To evaluate the impact of baseline resistance detected through PBMC GRT on virological rebou...

Topics

Adult
Anti-Retroviral Agents
CD4 Lymphocyte Count
DNA, Viral
Drug Resistance, Viral
Drug Substitution
Female
Genotype
Genotyping Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

HIV Infections

HIV-1

Humans

Leukocytes, Mononuclear

Male

Microbial Sensitivity Tests

Middle Aged

Prognosis

Proviruses

Source

Open in PubMed

Identifiers

PMID: 29738896
DOI: 10.1016/j.jcv.2018.04.001

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-29738896-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.