Article
Cellular HIV-1 DNA levels in drug sensitive strains are equivalent to those in drug resistant strains in newly-diagnosed patients in Europe.
PloS one - 8 Jun 2010
Demetriou Victoria L, van de Vijver David A M C, Kousiappa Ioanna, Balotta Claudia, Clotet Bonaventura, Grossman Zehava, Jørgensen Louise B, Lepej Snjezana Z, Levy Itzchak, Nielsen Claus, Paraskevis Dimitrios, Poljak Mario, Roman Francois, Ruiz Lidia, Schmidt Jean-Claude, Vandamme Anne-Mieke, Van Laethem Kristel, Vercauteren Jurgen, Kostrikis Leondios G
Abstract excerpt
BACKGROUND: HIV-1 genotypic drug resistance is an important threat to the success of antiretroviral therapy and transmitted resistance has reached 9% prevalence in Europe. Studies have demonstrated that HIV-1 DNA load in peripheral blood mononuclear cells (PBMC) have a predictive value for diseas...
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