Article
Genotypic susceptibility score (GSS) and CD4+ T cell recovery in HIV-1 patients with suppressed viral load.
The Journal of antimicrobial chemotherapy - 1 Feb 2017
Gonzalez-Serna Alejandro, Glas Arie C, Brumme C J, Poon Art F Y, Nohpal De La Rosa Adriana, Mudrikova Tania, Dias Lima Viviane, Wensing Annemarie M J, Harrigan Richard
Abstract excerpt
OBJECTIVES: HIV drug resistance, measured by the genotypic susceptibility score (GSS), has a deleterious effect on the virological outcome of HIV-1-infected patients. However, it is not known if GSS retains any predictive value for CD4 recovery in patients with suppressed viral load. METHODS: Four hundred and six patients on virological failure (>500 copies/mL) with GSS : <6 months prior to switch therapy who...
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