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Article

Clonally-related primary ALK rearranged adenocarcinoma and associated metastatic lesions.

Thoracic cancer - 1 Jul 2018

Zhu You-Cai, Deng Yun-Te, Wang Wen-Xian, Xu Chun-Wei, Zhuang Wu, Du Kai-Qi

Abstract excerpt

ALK rearrangement is a driver gene in non-small cell lung cancer (NSCLC). ALK-positive tumors are sensitive to ALK-tyrosine kinase inhibitors (TKIs). The detection of key driver genes is crucial to enable personalized treatment. Different histomorphological patterns have different driver genes. Herein, we report the case of a 42-year-old male patient diagnosed with adenocarcinoma with different histomorphologies...

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Source

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Identifiers

PMID: 29737033
DOI: 10.1111/1759-7714.12648
PMCID: PMC6026599

Genes

ALK
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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