The clinicopathological significance of ALK rearrangements and KRAS and EGFR mutations in primary pulmonary mucinous adenocarcinoma.

doi:10.1007/s13277-015-3331-4

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Article

The clinicopathological significance of ALK rearrangements and KRAS and EGFR mutations in primary pulmonary mucinous adenocarcinoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2015

Qu Yang, Che Nanying, Zhao Dan, Zhang Chen, Su Dan, Zhou Lijuan, Zhang Lili, Wang Chongli, Zhang Haiqing, Wei Lixin

Abstract excerpt

Primary pulmonary mucinous adenocarcinoma (PPMA) is one of the important subtypes of lung adenocarcinoma. Detection of anaplastic lymphoma receptor tyrosine kinase (ALK) rearrangements and of KRAS and epidermal growth factor receptor (EGFR) mutations will help in diagnosing and predicting treatment outcome. The aim of this study was to investigate the clinicopathological significance of ALK rearrangements, KRAS...

Topics

Adenocarcinoma
Adenocarcinoma of Lung
Adenocarcinoma, Mucinous
Adult
Aged
Anaplastic Lymphoma Kinase
Carcinoma, Non-Small-Cell Lung
DNA Mutational Analysis
ErbB Receptors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Female

Gene Expression Regulation, Neoplastic

Humans

Lung Neoplasms

Male

Middle Aged

Mutation

Neoplasm Staging

Prognosis

Source

Open in PubMed

Identifiers

PMID: 25813151
DOI: 10.1007/s13277-015-3331-4

Genes

ALK
KRAS
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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