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Article

PKC Dependent p14ARF Phosphorylation on Threonine 8 Drives Cell Proliferation.

Scientific reports - 4 May 2018

Fontana Rosa, Guidone Daniela, Sangermano Felicia, Calabrò Viola, Pollice Alessandra, La Mantia Girolama, Vivo Maria

Abstract excerpt

ARF role as tumor suppressor has been challenged in the last years by several findings of different groups ultimately showing that its functions can be strictly context dependent. We previously showed that ARF loss in HeLa cells induces spreading defects, evident as rounded morphology of depleted cells, accompanied by a decrease of phosphorylated Focal Adhesion Kinase (FAK) protein levels and anoikis. These data,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29728595
DOI: 10.1038/s41598-018-25496-4
PMCID: PMC5935756

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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