Article
Mendelian randomization analysis of cholesteryl ester transfer protein and subclinical atherosclerosis: A population-based study.
Journal of clinical lipidology - 1 Jan 2000
Christen Tim, Trompet Stella, Noordam Raymond, Blauw Lisanne L, Gast Karin B, Rensen Patrick C N, Willems van Dijk Ko, Rosendaal Frits R, de Mutsert Renée, Jukema J Wouter
Abstract excerpt
BACKGROUND: Several trials to prevent cardiovascular disease by inhibiting cholesteryl ester transfer protein (CETP) have failed, except Randomized EValuation of the Effects of Anacetrapib through Lipid-modification. Thus far, it is unclear to what extent CETP is causally related to measures of atherosclerosis. OBJECTIVE: The aim of the article was to study the causal relationship between genetically determined...
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